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The three SSP enzymes (PHGDH, PSAT, and PSPH) are all highly expressed in various cancers to meet the large serine demand for survival (Locasale et al., 2011

After centrifugation at 13,000 rpm for 10 min at 4C, 200 l of the supernatant was transferred to a new tube and was subjected to acid hydrolysis by adding 600 l 1 M HCl and incubation at 94C for 2 h

By collectively analyzing multidimensional data and dynamically simulating SQORs regulatory network, we can ultimately elucidate SQORs complex roles in health and disease and translate this knowledge into new strategies to benefit both the environment and human health

Under alkaline conditions, Fe(II) can undergo spontaneous oxidation to Fe(III), creating an environment favorable for vitamin C-enhanced TET activity (Hore et al