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5A), cumulatively, Actinobacteria was the most abundant (42.24% 13.86%), followed by Firmicutes (35.38% 11.81%), Bacteroidetes (17.84% 6.71%), Euryarchaeota (2.83% 1.63%) and Proteobacteria (1.23% 1.76%), which explained the 99.5% of the phylum-level bacterial diversity

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To investigate effective nucleic acid therapy with smaller doses, a modified nucleic acid was prepared based on the seed sequence of miR-29a

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