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doi:10.2147/dddt.S471525

Nonsteroidal anti-inflammatory drugs (called NSAIDs, including aspirin, diclofenac, and ibuprofen) and acetaminophen, like other medications, have side effects

However, despite the improvements in folate production by microorganisms that have been achieved, the industrial microbial production of folate is still far from being economically feasible due to very low yields