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Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy

We found that OLA significantly decreased several L-carnitine metabolites levels in FES patients, including 2-octenoylcarnitine, 11z-octadecenylcarnitine, 9-decenoylcarnitine and L-palmitoylcarnitine

Under the combined action of these mechanisms, foam cell formation proliferates, providing a material basis for the development of atherosclerotic plaques

Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest