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[29]Current Patent Assignee: NITROMED - US5994294, 1999, A

May 20, 1953

Advances in Neurobiology, vol 4

In multiple oxidative stress models of retinal degeneration, elevated GPX4 expression has been shown to protect photoreceptors and RPECs, suggesting that increasing GPX4 expression may represent a potential gene therapy approach for patients with AMD (47, 48)