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First, the acceleration of early improvement is clinically meaningful for patients with time-sensitive goals

As Sherman and colleagues note, RWE can leverage data already collected during routine care, reducing both the time and expense required to generate evidence compared with initiating new trials

PMID: 35125818 | doi:10.3748/wjg.v28.i1.23

Mitochondrial metabolism serves a dual role in the cardiovascular system: it is the primary energy source for cardiomyocytes and a central integrator of overall cardiac health, and its dysfunction is a key driver of disease pathogenesis [128]

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