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Snail, a transcriptional repressor, was overexpressed in CRC cells and induced transdifferentiation of 3T3 fibroblasts to TAFs, endowing resistance to 5-FU and paclitaxel

Here's what researchers need to know: Reconstitution Allow the vial to reach room temperature before opening Use bacteriostatic water (BAC water) for reconstitution Add water slowly down the side of the vial - never inject directly onto the powder Gently swirl to dissolve - never shake vigorously Solution should be clear and colorless For step-by-step instructions with photos, see our complete reconstitution guide

IRE1 activation leads to the splicing of XBP1, which upregulates genes involved in protein folding and ERAD