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4.5.1 Angiogenesis and novel factors involved in the regulation of MB spreading The TME is responsible for the presence of several growth factors that can allow the generation of new blood vessels, such as vascular endothelial growth factor (VEGF) that in turn are essential for the growth and possible spreading of cancer cells (237, 238)

Galanin stimulates rat pituitary growth hormone secretion in vitro

This damage, known as oxidative stress, produces a domino effect in which the presence of free radicals attracts the electrons contained in the molecules of our cells, destabilizing the molecules and turning them into free radicals themselves

doi: 10.1016/j.actatropica.2020.105355 [DOI] [PMC free article] [PubMed] [Google Scholar] 327

The NMR data were acquired at the National Centre for Biological Science-Tata Institute of Fundamental Research NMR Facility