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There is an autosomal recessive cytochrome b -negative form of CGD due to defects in the -subunit of cytochrome b 245 (gene symbol CYBA ), also called p22-PHOX or NOX1

JCI Insight 5, (2020), Application(s): WB, Abstract Particulate Matter (PM2.5) from Biomass Combustion Induces an Anti-Oxidative Response and Cancer Drug Resistance in Human Bronchial Epithelial BEAS-2B Cells.: Merk, R., Heelbach, K., et al

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Hence stated that small molecule, REV-ERB agonists inhibit autophagy in cancer (Sulli et al., 2018)