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[DOI] [PubMed] [Google Scholar] 30.Thorpe S.J., Heath A., Blackmore S., Lee A., Hamilton M., OBroin S., Nelson B.C., Pfeiffer C

While Vitamin B12 is a naturally occurring nutrient that is generally considered very safe even in high doses, it is still a medical treatment

Users should work with qualified healthcare providers for monitoring and should report any unusual symptoms

References Warburg, O

These results collectively indicate that Sirt1 is indispensable for NNMT-mediated regulation of glucose metabolism, and both NNMT and MNAM have the ability to upregulate Sirt1 expression