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Moreover, cyclooxygenase inhibitors, which suppress prostaglandin E2 synthesis, have been shown to reduce fungal biofilm formation, highlighting their potential as adjunctive agents in antifungal therapy ( 4.4 Antifungal drugs targeting metabolic pathways and enzymes Fungal metabolism involves a wide array of biochemical pathways essential for growth, survival, and virulence, including N-acetylglucosamine utilization, trehalose metabolism, lipid biosynthesis, energy production, and intracellular transport (Pan et al., 2018

doi: 10.1016/j.redox.2017.11.001 191 SuiXZhangRLiuSDuanTZhaiLZhangMet al

There is very limited evidence to suggest that antioxidants in grape seed extract may help maintain healthy blood pressure and improve circulation

Metabolic labeling techniques, which employ chemically tagged metabolic precursors, enable dynamic tracking and enrichment of crotonylation, offering spatiotemporally resolved tools to investigate its biological functions [169]