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At 18 months of follow up, pirtobrutinib demonstrated superior median PFS with 14 months versus 8.7 months as assessed by an Independent Review Committee

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However, at the transcriptional level, THC increased CYP1A1 mRNA (Roth et al., 2001)

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These combined factors result in the contamination of freshwater resources, which subsequently acts as a critical vector for exposure in both wildlife and humans through the ingestion of contaminated water and the food chain 6