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see Additional file 1: Table S5)

Nrf2 is responsible for regulating the transcription of many key components within the ferroptosis pathway, 562 and targeting Nrf2 has emerged as a novel strategy for preventing and treating AD

Rocca C, Bartolo AD, Granieri MC, Rago V, Amelio D, Falbo F, Malivindi R, Mazza R, Cerra MC, Boukhzar L, Lefranc B, Leprince J, Anouar Y, Angelone T (2022) The antioxidant selenoprotein T mimetic, PSELT, induces preconditioning-like myocardial protection by relieving endoplasmic-reticulum stress

3.65 (95% CI: 3.04.3) and 2.02 (95% CI: 1.162.87), respectively, compared to the PTX group (Fig

Th1 and Th17 cells secrete cytokines that disrupt the tight junctions of the bloodbrain barrier (BBB), allowing inflammatory factors such as TNF, IL-1, and IL-6 to enter the brain, thereby accelerating the progression of AD