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D/L-glucose competition experiment To measure the competitive effects of CDr17 with D/L-glucose, the media of M1 macrophages differentiated from RAW264.7 cell was changed into DMEM, no glucose (Gibco) with 10% Heat-Inactivated Fetal Bovine Serum (Gibco) and 1% Penicillin Streptomycin (WELGENE), containing 0, 20, 60 mM of D/L-glucose

Possible mild discomfort and swelling post-treatment

Although it can be easily manipulated in large quantities, it can lead to certain metabolites and metabolic pathways that cannot be determined

Results and discussion Synthesis and characterization of copolymer The Gu, Hb and DSMA monomers were synthesized according to the literature [29, 30]