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Jerne recalled 'the air was filled with phage particles that Delbrck had picked out as one of the weakest spots in the armour behind which Nature guards her secrets' (Jerne 1966)

Several in vitro and in vivo therapeutic studies have shown that SOD2 lipophilic mimic, Mn (III) meso-tetrakis (N-n-hexylpyridinium-2-yl) porphyrin, (H2O) MnTnHex-2-PyP5 + (MnHex) can cross the BBB and accumulate in mitochondria than cytosol (Leu D et al., 2017

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Het, single heterozygous defect

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