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Many also demonstrate inherent biocompatibility, reducing the potential for ocular toxicity compared to conventional TB drugs ( The structural versatility of natural compounds enables medicinal chemistry optimization to enhance solubility, tissue penetration, and antimicrobial potency (Mazlun et al., 2019)

Its primary mechanisms include: Actin regulation: TB-500 upregulates actin, a key structural protein in cells

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2 Discussion Zn deficiency is common in IBD patients and is associated with worse clinical outcomes, including increased hospitalizations, higher risk of complications, and disease severity