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Many regions of the brain express receptors for GH, IGF-1, and ghrelin

When these peptides are combined, the resultant cocktail of peptides works synergistically to stimulate the pituitary gland to produce a greater amount of growth hormone and maximise its effects

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In the pathogenesis of cardiovascular diseases, excessive ROS production disrupts mitochondrial function, amplifies inflammatory responses, and induces significant cellular damage, such as myocardial fibrosis, cardiomyocyte apoptosis, and extracellular matrix degradation [127, 128]