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Glutathione responsive nanomedicine leverages tumor redox imbalance for targeted cancer theranostics Discover Oncology Springer Nature Link Multi Omics Analysis Reveals Chronic Cisplatin Exposure Is Associated with Metabolic Rewiring Toward Glutathione Metabolism to Support Redox Adaptation in High Grade Serous Ovarian Cancer Role of Glutathione in Cancer: From Mechanisms to Therapies Glutathione: a naturally occurring tripeptide for functional metal nanomaterials Chemical Science (RSC Publishing) DOI:10.1039 D4SC08599J Relationship between Glutathione Dependent Enzymes and the Immunohistochemical Profile of Glial Neoplasms

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The DONEPEZOX trial, as a proof-of-concept, randomized, triple-blind, and multicenter study, will be the first clinical trial to evaluate the efficacy and safety of donepezil in oxaliplatin for gastrointestinal cancer-induced severe peripheral neuropathy (OIPN), with the response rate in the donepezil group (neuropathy grade reduction according to the QLQ-CIPN20 sensory score) as the primary endpoint [168]