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Both modulate fundamental biological ageing pathways yet they do so through substantially different molecular mechanisms, at different tissue levels, and with distinct research strengths

[PMC free article: PMC3540842] [PubMed: 22649206] 895

Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later

The membranolytic attack complex deposition on the intramuscular capillaries leads to osmotic lysis of the endothelial cells and necrosis of the capillaries