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Description

The damage is not always immediately apparent, which means the condition can progressively worsen, leading to heart failure or other serious complications over time

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Animal models remain indispensable in preclinical evaluations, providing critical insights into the efficacy and safety of nanomaterials

GSH conjugation begins with a reaction catalysed by glutathione-S-transferases (GSTs)

GSH can also regulate the expression of genes by modulating the redox state of proteins and transcription factors, but this mechanism is yet poorly understood (Dietz 2014