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Side Effects and Contraindications : Because morphine binds to opioid receptors in the brain and spinal cord, with liver and gut metabolism and a slow onset of action, patients often experience the following side effects (57): Constipation Nausea Vomiting Sedation Dizziness Respiratory depression Pruritus Sweating Dysphoria/Euphoria Dry mouth Anorexia Spasms of the urinary and biliary tract Contraindications of morphine are: Known hypersensitivity or allergy to morphine

Branched Chain Amino Acids (BCAAs): Essential amino acids (leucine, isoleucine, and valine) important for muscle protein synthesis and exercise performance

Diabetic neuropathy often affects the feet and legs first, although it can also affect the hands