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Tracheotomy was performed and the animals were allowed to breathe spontaneously through the tracheal cannula
Injectable forms are often considered more effective for systemic targets (tendons, joints, muscles) because they bypass digestive breakdown and provide higher bioavailability
Current therapeutic development focuses on either recombinant protein formulations (Jocasta Neurosciences JN-0413) or mRNA-based approaches to stimulate endogenous production (Klothea Bio)
Riddy, D
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