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Proc Natl Acad Sci USA 116(23):1140811417

Because of how the injections deliver B12, you may experience some discomfort , redness, bruising, inflammation, itching, or tenderness near the injection site

For oral administration in mice, NR and NMN are first metabolized by the liver or GI tract into NAM, which can then be taken up by other tissues

Many users notice skin feels more hydrated and looks slightly more radiant within the first two weeks