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The copper ion binds to the peptide through a square-planar pyramid configuration, creating an extraordinarily stable complex with a binding affinity (pK = 16.44) approximately 10 million times higher than other tripeptides

The studies documenting hair-relevant effects DPC proliferation, follicle elongation, stem cell recovery used direct tissue contact, which topical application most closely replicates

There is also laboratory research on related copper peptides showing effects on human hair follicles and dermal papilla cells

Gonadorelin Gonadorelin is a synthetic gonadotropin releasing hormone used to induce LH and FSH release

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