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Although SIRT1 mRNA was not significantly changed, SIRT1 protein expression was elevated ( SIRT1 expression and stability

Davies MJ, Bergenstal R, Bode B, Kushner RF, Lewin A, Skjoth TV, et al

These include L-glutamic acid (20.3 fold enrichment), glycine (29.6 fold enrichment), pyroglutamic acid (2.9 fold enrichment) and putrescine (10.3 fold enrichment)