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J Saudi Chem Soc 2020

The plasma levels of IL-1, IL-6, and TNF- in rats treated with cardamomin were markedly inhibited

134 Therefore, CK2 inhibitor has been considered as an indirect inhibitor of claudin-2 (Figure 3b)

Every dose tier outperformed placebo, but the magnitude of difference between the lowest and highest tiers reveals exactly how dose-dependent the response curve is