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KPV increases blood flow by activating endothelial nitric oxide synthase (eNOS), which increases the generation of nitric oxide, a potent vasodilator that relaxes blood vessels and reduces blood pressure

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Some patients have had letters stating the GPs are following advice from Public Health England, NHS England, CCGs, etc and some even say advice from Europe

Intramuscular treatment should be re-instated at the first sign of a recurrence of neurological symptoms in a patient previously changed to an oral formulation