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A study that followed 7,863 subjects with a history of heart attack or unstable angina for six years found higher D-dimer levels were associated with a higher risk of major coronary artery and cardiovascular events, as well as VTE

In Drosophila , both overexpression and knockdown of HDAC4 impair memory, suggesting that HDAC4 is both a repressor when in excess and essential for normal memory function [47]

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Table 2 Primer sequences of target and reference genes

These results suggest that the inhibition of GLUD1 methylation decreases its protein stability