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Emerging evidence suggests that HO-1 exerts a regulatory function in the pathophysiological process of VaD by modulating the ferroptosis pathway (Fu et al., 2023

FIGURE 9 The tissue sections of the heart from all groups, including the control, sham, I/R, I/R + GSH, I/R + GO@GSH, and I/R + GO@GSH-FA, showed normal myocardial architecture without any signs of inflammation, necrosis, or other pathological changes

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This study is also the first to report the direct interaction between luteolin and GPVI by SPR