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Donors should report any recent or ongoing side effects from tirzepatide, particularly gastrointestinal symptoms, changes in blood pressure, episodes of hypoglycemia, or significant weight changes

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Additional Therapies Leukotriene modifiers, oral N -acetylcysteine, inhaled glutathione, inhaled anticholinergic bronchodilators, inhaled beta 2 -agonist bronchodilators, oral antipseudomonal antibiotics, oral antistaphylococcal antibiotics, and other inhaled antibiotics are not recommended for chronic use in CF due to lack of sufficient evidence