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Mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving cerebral blood flow, and modulation of dopamine and serotonin systems

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While rare, taking too much vitamin A, D, or E can lead to potentially harmful side effects ( Alternatively, taking high doses of non-synthetic vitamin K seems to be relatively harmless, which is why an upper intake level (UL) has not been set for this nutrient ( Upper intake levels are set to indicate the maximum dose of a nutrient thats unlikely to cause harm for nearly all people in a general population ( SUMMARY Water-soluble vitamins are readily excreted from the body, while fat-soluble vitamins can be stored in tissues