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However, comprehensive long-term human safety data does not exist

It depends on your goals and, where relevant, your lab values

[11] In practice, the benefit of treating a true B deficiency in pregnancy, preventing anemia and neurological injury, is considered to far outweigh any theoretical risks, under the guidance of a healthcare professional

-Tocopherol Supplementation of Allergic Female Mice Augments Development of CD11c + CD11b + Dendritic Cells in Utero and Allergic Inflammation in Neonates

When autonomic neuropathy is diabetic in etiology, use the E-code combination (E11.43 = Type 2 DM with diabetic autonomic neuropathy)