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PubMed Dunaiski V, Dunshea FR, Walton PE, Goddard C Long [R3] insulin-like growth factor-I reduces growth, plasma growth hormone, IGF binding protein-3 and endogenous IGF-I concentrations in pigs

doi: 10.1161/01.HYP.27.1.32 189 MardaniFMahmoudiMEsmaeiliSAKhorasaniSTabasiNRastinM

Results Across mechanistic endpoints, LC was associated with reductions in inflammatory markers, oxidative stress indices, and cardiac injury biomarkers, with several trials noting improvements in left-ventricular function and lipid profiles