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The role of senescence-associated histone modification changes in the senescence regulatory mechanisms has been broadly explored

Drugs 24 , 725733 (2015)

Anderson et al., 1987

Although the XGB-based model (ST-XGB) achieved the highest mean AUROC, its lower recall led us to emphasize the LightGBM variant (ST-LGBM) for subsequent label-specific analyses, where maximizing recall is critical for comprehensive odor profiling and safety

In vivo studies have shown that the combination of ASP and cisplatin can significantly inhibit the growth of transplanted tumors, while having no obvious toxicity to normal tissues and organs, showing a good safety profile (184)