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for 5 min at 2300 g to pellet erythrocytes, and the plasma was transferred to clean tubes

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Other cell types, such as macrophages and erythropoietic cells have special requirements for iron handling, as they accommodate the large iron fluxes associated with the recycling of iron from senescent red blood cells and hemoglobin synthesis, respectively

The elevated oxalate levels increase inflammation and fibrosis.[ref] Related article : Fatty liver disease NLRP3 inflammasome activation: The NLRP3 inflammasome is activated by increased ROS and calcium oxalate crystals