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Research protocols must account for potential beneficial roles of some senescent cells in wound healing and immune responses, requiring careful consideration of administration timing and duration in experimental designs

doi: 10.3390/ijms19010316 143 WeiL.MartinJ

Currently, some prospective animal studies have begun exploring schemes combining drug administration with advanced biomaterials, yielding positive preliminary results, but their long-term efficacy and safety still require evaluation in larger-scale, in-depth studies

These cells showed resistance to Bevacizumab in vitro and also had higher levels of AKT phosphorylation

doi: 10.1038/s41420-025-02711-6