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Second, we are also providing a second, modified version of this example to reflect a situation in which the severe supply chain disruption rebate reduction is granted for the same calendar quarter as the Part B rebatable biosimilar biological product is currently in shortage, and the application of the shortage reduction precedes application of the severe supply chain disruption reduction due to the timing of the shortage and submission of the rebate reduction request, illustrated as Example 2 in the table

We also proposed in the CY 2025 PFS proposed rule to revise 414.1367(c)(1) such that each MIPS eligible clinician, group, or APM Entity APM that elects to report the APP would choose to report either the APP quality measure set or the APP Plus quality measure set

For peptides, HPLC is widely used for separation and analysis, and reversed-phase HPLC is a common technique in peptide purification and analytical workflows [14]