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The acute form of oxaliplatin-induced CIPN tends to weaken between treatment cycles, but prolonged exposure to this drug often leads to the development of a severe chronic form of CIPN

Abstract Sickle cell disease (SCD) is a genetic disorder predominantly affecting individuals of African descent, with a significant global health burden

Inoltre, sono stati sintetizzati due copolimeri salificati di stirene e stirene solfonato (PSS), a diversi rapporti molari, che sono stati utilizzati come anioni per la realizzazione dei PILs 1-metil-3-esadecil imidazolo polistirenestirene solfonato 75:25 (EDmim + PSS - 75:25) e 1-metil-3-esadecil imidazolo polistirene-stirene solfonato 90:10 (EDmim + PSS - 90:10)

First-in-human studies of pharmacokinetics and safety of utreloxastat (PTC857), a novel 15-lipooxygenase inhibitor for the treatment of amyotrophic lateral sclerosis

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