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Single nucleotide variants Single nucleotide variants (SNVs) represent the most prevalent type of mtDNA alterations identified in malignant tumors, generally referring to single-nucleotide substitutions in the mitochondrial genome, including transitions and transversions, which predominantly occur in protein-coding genes critical for OXPHOS [125]

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The Histidine-25-Arginine Mutation in the Rice MACPF Protein OsCAD1 Induces Cell Death and Activates Defense Responses in the Lesion Mimic Mutant spl17

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