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11 In a small study, participants with mild to moderate acne who took 500 mg of oral glutathione daily for 4 weeks saw a reduction in acne severity and improved skin condition , with no major side effects

Mutations in genes like TP53 and DNA repair genes can disrupt cell cycle regulation and impair the cells ability to repair DNA damage, resulting in genetic errors (142, 143)

Beyond this catalytic role, GSTP1 exerts non-enzymatic regulatory functions: it physically interacts with the c-Jun N-terminal kinase (JNK) to suppress kinase activity and limit apoptosis under non-stress conditions

Santos LO, Gonzales TA, Ubeda BT, Alegre RM (2007) Influence of culture conditions on glutathione production by Saccharomyces cerevisiae

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