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Description

Role of gut microbiota in type 2 diabetes pathophysiology

We propose that PYC, a pine bark polyphenol extract, can modulate the structure of gut microbial community to increase the expression of SCFAs, GABA and 5-HT targeting the gut-brain axis as well as regulating synaptic protein synthesis and promoting plasticity, thus becoming a powerful natural drug candidate for the treatment of NDDs

Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver