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Description

J Pediatr 1987;111(4):525-33

R.ChitneniS

The execution of ferroptosis is counterbalanced by a sophisticated array of cellular defense systems, such as the system Xc/glutathione (GSH)/GPX4 axis and the NAD (P)H-FSP1-CoQH pathway, which work in concert to neutralize lipid peroxides and maintain redox homeostasis [5,6,7]