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Deficiently of vitamin B12 can lead to abnormal neurologic and psychiatric symptoms including ataxia (shaky movements and unsteady gait), muscle weakness, spasticity, incontinence, hypotension, vision problems, dementia, psychosis, and mood disturbances

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105 Following that, these sequences are altered to produce a list of potential candidates which might be able to interact with a certain target protein, thereby blocking non-specific interaction with other proteins

A significant reduction of the DTI-ALPS index was observed from the acute phase to the 3-month follow-up MRI [1.48 (0.18) vs 1.32 (0.17), p 0.001