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Considering the above, an effective way of avoiding the exposure of the gut microbiota to acetyl-l-carnitine is its parenteral administration

L-carnitine supplementation in arm I patients was taken after feed in the form of tablets or dissolved tablets with a daily dose of 50 mg/kg/day, up to a maximum of 2 g/day, once per day 8,13

W.IV (2006)

L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPAR signaling

However, compared with the intensive mechanistic studies of carnitine in mammals, the majority of the studies of carnitine in fish have only focused on the effects of carnitine on the fishs growth and body composition, whereas studies on the systemic regulation of nutritional metabolism by carnitine in fish, and the underlying mechanisms, are lacking