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4.1.2 PI3K/AKT inhibitors Activation of phosphoinositide 3-kinase (PI3K) can lead to the phosphorylation and subsequent inactivation of Bad and caspase-9 [111]

In a subsequent experiment, competition between SemDAPH and mGppNHp-bound Cdc42 was evaluated by rapidly mixing 1 M of the pre-prepared complex of mGppNHp-bound Cdc42 and N-WASP BR-GBD with 1 M of SemDAPH