Another study involving 28 CDLBP patients compared the clinical outcomes of IRFT (13 patients) to a placebo treatment (15 patients) and found that IRFT was not effective in reducing CDLBP (Barendse et al., 2001)
Moreover, other genetic traits, such as the functional deficiencies in cobalamin-dependent methionine synthase described above, could contribute to an increased relative risk of cardiovascular disease, but their respective contributions are not yet determined

Macromolecule Content Total Structure Weight: 460.38 kDa Atom Count: 36,037 Modeled Residue Count: 4,073 Deposited Residue Count: 4,100 Unique protein chains: 1 Experimental Data Method: X-RAY DIFFRACTION Resolution: 2.01 R-Value Free: 0.192 (Depositor), 0.190 (DCC) R-Value Work: 0.171 (Depositor), 0.168 (DCC) R-Value Observed: 0.171 (Depositor) Unit Cell : Software Package: Revision History (Full details and data files) Version 1.0: 2001-02-23 Type: Initial release Version 1.1: 2011-05-08 Changes: Version format compliance Version 1.2: 2011-07-13 Changes: Version format compliance Version 2.0: 2018-01-17 Changes: Advisory, Atomic model, Data collection, Derived calculations Version 2.1: 2018-02-07 Changes: Source and taxonomy Version 2.2: 2024-05-01 Changes: Advisory, Data collection, Database references, Derived calculations, Refinement description

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Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin -4 in the dystrophin deficient mouse