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Description

Cerebrospinal-fluid-contacting neurons

After TIGAR overexpression, the expression levels of Beclin-1 and LC3II decreased significantly, and P62 expression increased, while the inhibition of TIGAR gene expression in mice had the opposite effect

doi: 10.1016/S0966-842X(01)02035-2 45 FiracativeC.GresslerA

Whether this retained iron transfers to adjacent neurons through gap junctions (Cx43), acting as a messenger connecting necroptosis and ferroptosis, remains unknown