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89,90,91,92,93 These cytokines play a central role in orchestrating the inflammatory response by recruiting additional immune cells and amplifying the proinflammatory cascade

98 JohnsL.AllenP.ValliI.Winton-BrownT.BroomeM.WoolleyJ.et al

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In this study, we demonstrated that the transcription factor LcERF107 activated the expression of genes related to oxygen glutathione metabolism and significantly enhanced the activities of antioxidant enzymes, which led to the accumulation of ROS and reactive oxygen species in the body, thus improving the freezing tolerance of blue honeysuckles under low-temperature stress

(2017) further supported rutins antidepressant potential by observing a dose-dependent decrease in immobility time during the tail suspension test (TST) in mice treated with rutin (Yushau et al., 2017) (Figure 3)