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The activity of dipeptidase can be assayed with a HPLC method using glycyl-D-phenylalanine as described by Littlewood et al

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10.1161/circresaha.115.306301 57 GorriniC.HarrisI

One proposed mechanism is the activation of matrix metalloproteinase-9 by homocysteine, which leads to disruption of the blood-retinal barrier and increased vascular permeability in the retina [61]

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