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It appeared as the first in-line synthetic peptide that specifically triggered growth hormone release in a dose-dependent manner, both in cell cultures and in living organisms

Week 13+ often involves a maintenance dose or a planned break (24 weeks off) to prevent receptor desensitization

It was demonstrated that in males the reduction of mean meal number due to a GhrR knockout was significant while in females no significant mean meal number reduction was observed

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Mass spectrometrical analysis of recombinant human growth hormone (Genotropin) reveals amino acid substitutions in 2% of the expressed protein